PDB entry 3byu
View 3byu on RCSB PDB site
Description: co-crystal structure of Lck and aminopyrimidine reverse amide 23
Class: transferase
Keywords: Lck, Kinase domain, Alternative splicing, ATP-binding, Chromosomal rearrangement, Cytoplasm, Disease mutation, Host-virus interaction, Lipoprotein, Membrane, Myristate, Nucleotide-binding, Palmitate, Phosphoprotein, Proto-oncogene, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase
Deposited on
2008-01-16, released
2008-09-16
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-06-09, with a file datestamp of
2009-06-05.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.232
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Proto-oncogene tyrosine-protein kinase LCK
Species: Homo sapiens [TaxId:9606]
Gene: LCK
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3byua_ - Heterogens: AM6, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3byuA (A:)
qtqkpqkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspda
flaeanlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldm
aaqiaegmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregakfpi
kwtapeainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdn
cpeelyqlmrlcwkerpedrptfdylrsvledfftat
Sequence, based on observed residues (ATOM records): (download)
>3byuA (A:)
kpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaean
lmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiae
gmafieernyihrdlraanilvsdtlsckiadfglkfpikwtapeainygtftiksdvws
fgillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmrlcwkerpedrp
tfdylrsvledfftat