PDB entry 3apn

View 3apn on RCSB PDB site
Description: Crystal structure of the human wild-type PAD4 protein
Class: hydrolase
Keywords: alpha/beta-propeller, immunoglobulin-like, arginine citrullination, hydrolase, protein-arginine deiminase, post-translational modification, Calcium binding, histone binding, benzoyl-L-arginine amide binding, nucleus
Deposited on 2010-10-19, released 2011-01-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-04-11, with a file datestamp of 2012-04-06.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.246
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein-arginine deiminase type-4
    Species: Homo sapiens [TaxId:9606]
    Gene: PADI4, PADI5, PDI5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UM07 (Start-665)
      • engineered mutation (84)
      • engineered mutation (114)
    Domains in SCOPe 2.08: d3apna1, d3apna2, d3apna3

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3apnA (A:)
gphmaqgtlirvtpeqpthavcvlgtltqldicssapedctsfsinaspgvvvdiahspp
akkkstgsstwpldpgvevtltmkaasgstgdqkvqisyygpktppvkallyltaveisl
caditrtgkvkptravkdqrtwtwgpcgqgaillvncdrdnlessamdceddevldsedl
qdmslmtlstktpkdfftnhtlvlhvarsemdkvrvfqatrgklsskcsvvlgpkwpshy
lmvpggkhnmdfyvealafpdtdfpglitltislldtsnlelpeavvfqdsvvfrvapwi
mtpntqppqevyacsifenedflksvttlamkakcklticpeeenmddqwmqdemeigyi
qaphktlpvvfdsprnrglkefpikrvmgpdfgyvtrgpqtggisgldsfgnlevsppvt
vrgkeyplgrilfgdscypsndsrqmhqalqdflsaqqvqapvklysdwlsvghvdefls
fvpapdrkgfrlllasprscyklfqeqqneghgeallfegikkkkqqkiknilsnktlre
hnsfvercidwnrellkrelglaesdiidipqlfklkefskaeaffpnmvnmlvlgkhlg
ipkpfgpvingrccleekvcslleplglqctfindfftyhirhgevhcgtnvrrkpfsfk
wwnmvp

    Sequence, based on observed residues (ATOM records): (download) 
    >3apnA (A:)
aqgtlirvtpeqpthavcvlgtltqldicssapctsfsinaspgvvvdiahstwpldpgv
evtltmkaasgstgdqkvqisyygpktppvkallyltaveislcaditrtgkvkqrtwtw
gpcgqgaillvncdrdldsedlqdmslmtlstktpkdfftnhtlvlhvarsemdkvrvfq
atrkcsvvlgpkwpshylmvpggkhnmdfyvealafpdtdfpglitltislldtsnlelp
eavvfqdsvvfrvapwimtpntqppqevyacslksvttlamkakcklticqdemeigyiq
aphktlpvvfdsdfgyvtrggldsfgnlevsppvtvrgkeyplgrilfgdscypsndsrq
mhqalqdflsaqqvqapvklysdwlsvghvdeflsfvpapdrkgfrlllasprscyklfq
eqqneghgeallfkqqkiknilsnktlrehnsfvercidwnrellkrelglaesdiidip
qlfklkefskaeaffpnmvnmlvlgkhlgipkpfgpvingrccleekvcslleplglqct
findcgtnvrrkpfsfkwwnmvp