PDB entry 2zb2

View 2zb2 on RCSB PDB site
Description: Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide
Class: transferase
Keywords: ALLOSTERIC SITE, ALLOSTERIC BINDING, Allosteric enzyme, Carbohydrate metabolism, Disease mutation, Glycogen metabolism, Glycogen storage disease, Glycosyltransferase, Nucleotide-binding, Phosphorylation, Pyridoxal phosphate, Transferase
Deposited on 2007-10-15, released 2008-09-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.3
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen phosphorylase, liver form
    Species: Homo sapiens [TaxId:9606]
    Gene: PYGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2zb2a_
  • Chain 'B':
    Compound: Glycogen phosphorylase, liver form
    Species: Homo sapiens [TaxId:9606]
    Gene: PYGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2zb2b_
  • Heterogens: GLC, MES, PLP, A46, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zb2A (A:)
gsmakpltdqekrrqisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalah
tvrdhlvgrwirtqqhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgl
dieeleeieedaglgngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqve
eaddwlrygnpweksrpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnnt
vntmrlwsarapndfnlrdfnvgdyiqavldrnlaenisrvlypndnffegkelrlkqey
fvvaatlqdiirrfkaskfgstrgagtvfdafpdqvaiqlndthpalaipelmrifvdie
klpwskaweltqktfaytnhtvlpealerwpvdlvekllprhleiiyeinqkhldrival
fpkdvdrlrrmslieeegskrinmahlcivgshavngvakihsdivktkvfkdfselepd
kfqnktngitprrwlllcnpglaeliaekigedyvkdlsqltklhsflgddvflrelakv
kqenklkfsqfleteykvkinpssmfdvqvkriheykrqllnclhvitmynrikkdpkkl
fvprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsklkviflenyrvslaekvi
patdlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenlfifgmridd
vaaldkkgyeakeyyealpelklvidqidngffspkqpdlfkdiinmlfyhdrfkvfady
eayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtikeyaqniwnvepsdlkisls
nesnkvngn

    Sequence, based on observed residues (ATOM records): (download) 
    >2zb2A (A:)
envaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtqqhyydkcpkr
vyylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedaglgngglgrlaa
cfldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpweksrpefmlpvh
fygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapndfgdyiqavld
rnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskfgagtvfdafpdq
vaiqlndthpalaipelmrifvdieklpwskaweltqktfaytnhtvlpealerwpvdlv
ekllprhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskrinmahlcivgshav
ngvakihsdivktkvfkdfselepdkfqnktngitprrwlllcnpglaeliaekigedyv
kdlsqltklhsflgddvflrelakvkqenklkfsqfleteykvkinpssmfdvqvkrihe
ykrqllnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmiiklitsvadvvnn
dpmvgsklkviflenyrvslaekvipatdlseqistagteasgtgnmkfmlngaltigtm
dganvemaeeageenlfifgmriddvaaldkkgyeakeyyealpelklvidqidngffsp
kqpdlfkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawntmvlkniaasgkfs
sdrtikeyaqniwnveps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zb2B (B:)
gsmakpltdqekrrqisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalah
tvrdhlvgrwirtqqhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgl
dieeleeieedaglgngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqve
eaddwlrygnpweksrpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnnt
vntmrlwsarapndfnlrdfnvgdyiqavldrnlaenisrvlypndnffegkelrlkqey
fvvaatlqdiirrfkaskfgstrgagtvfdafpdqvaiqlndthpalaipelmrifvdie
klpwskaweltqktfaytnhtvlpealerwpvdlvekllprhleiiyeinqkhldrival
fpkdvdrlrrmslieeegskrinmahlcivgshavngvakihsdivktkvfkdfselepd
kfqnktngitprrwlllcnpglaeliaekigedyvkdlsqltklhsflgddvflrelakv
kqenklkfsqfleteykvkinpssmfdvqvkriheykrqllnclhvitmynrikkdpkkl
fvprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsklkviflenyrvslaekvi
patdlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenlfifgmridd
vaaldkkgyeakeyyealpelklvidqidngffspkqpdlfkdiinmlfyhdrfkvfady
eayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtikeyaqniwnvepsdlkisls
nesnkvngn

    Sequence, based on observed residues (ATOM records): (download) 
    >2zb2B (B:)
envaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtqqhyydkcpkr
vyylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedaglgngglgrlaa
cfldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpweksrpefmlpvh
fygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapngdyiqavldrn
laenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkastvfdafpdqvaiqlnd
thpalaipelmrifvdieklpwskaweltqktfaytnhtvlpealerwpvdlvekllprh
leiiyeinqkhldrivalfpkdvdrlrrmslieeegskrinmahlcivgshavngvakih
sdivktkvfkdfselepdkfqnktngitprrwlllcnpglaeliaekigedyvkdlsqlt
klhsflgddvflrelakvkqenklkfsqfleteykvkinpssmfdvqvkriheykrqlln
clhvitmynrikkdpkklfvprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsk
lkviflenyrvslaekvipatdlseqistagteasgtgnmkfmlngaltigtmdganvem
aeeageenlfifgmriddvaaldkkgyeakeyyealpelklvidqidngffspkqpdlfk
diinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtike
yaqniwnveps