PDB entry 2z6k

View 2z6k on RCSB PDB site
Description: Crystal structure of full-length human RPA14/32 heterodimer
Class: replication
Keywords: full-length RPA14/32, ssDNA binding protein, OB-fold, Acetylation, Alternative splicing, DNA replication, Nucleus, Phosphorylation, Polymorphism
Deposited on 2007-08-03, released 2007-12-04
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.229
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2z6ka1
  • Chain 'B':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2z6kb1
  • Chain 'C':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2z6kc1
  • Chain 'D':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2z6kd1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2z6kA (A:)
mwnsgfesygsssyggaggytqspggfgspapsqaekksraraqhivpctisqllsatlv
devfrignveisqvtivgiirhaekaptnivykiddmtaapmdvrqwvdtddtssentvv
ppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlskansqpsagr
apisnpgmseagnfggnsfmpangltvaqnqvlnlikacprpeglnfqdlknqlkhmsvs
sikqavdflsneghiystvdddhfkstdae

    Sequence, based on observed residues (ATOM records): (download) 
    >2z6kA (A:)
raqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaap
mdvrqwvdntvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmv
lskansq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2z6kB (B:)
mwnsgfesygsssyggaggytqspggfgspapsqaekksraraqhivpctisqllsatlv
devfrignveisqvtivgiirhaekaptnivykiddmtaapmdvrqwvdtddtssentvv
ppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlskansqpsagr
apisnpgmseagnfggnsfmpangltvaqnqvlnlikacprpeglnfqdlknqlkhmsvs
sikqavdflsneghiystvdddhfkstdae

    Sequence, based on observed residues (ATOM records): (download) 
    >2z6kB (B:)
raqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaap
mdvrqwvdtvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvl
skansq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2z6kC (C:)
mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
neavkiihdfpqfyplgivqhd

    Sequence, based on observed residues (ATOM records): (download) 
    >2z6kC (C:)
vdmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmeplde
eisgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgiv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2z6kD (D:)
mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
neavkiihdfpqfyplgivqhd

    Sequence, based on observed residues (ATOM records): (download) 
    >2z6kD (D:)
vdmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmeplde
eisgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgiv