PDB entry 2yee
View 2yee on RCSB PDB site
Description: hsp90 inhibitors and drugs from fragment and virtual screening
Class: chaperone
Keywords: pu3, ATPase, chaperone, stress response, nucleotide-binding, ATP-binding, phosphoprotein, phosphorylation
Deposited on
2011-03-25, released
2011-06-15
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-08-31, with a file datestamp of
2011-08-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.23807
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P07900
- conflict (31)
- conflict (229)
Domains in SCOPe 2.08: d2yeea_ - Heterogens: SO4, 2EC, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2yeeA (A:)
mghhhhhhhhhhssghiddadkhmdqpmeeehvetfafqaeiaqlmsliintfysnkeif
lrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadli
nnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawes
saggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfqgypitlfvek
erdkevsddeae
Sequence, based on observed residues (ATOM records): (download)
>2yeeA (A:)
hvetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfqgypitlfve