PDB entry 2yee

View 2yee on RCSB PDB site
Description: hsp90 inhibitors and drugs from fragment and virtual screening
Class: chaperone
Keywords: pu3, ATPase, chaperone, stress response, nucleotide-binding, ATP-binding, phosphoprotein, phosphorylation
Deposited on 2011-03-25, released 2011-06-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-08-31, with a file datestamp of 2011-08-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.23807
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07900
      • conflict (31)
      • conflict (229)
    Domains in SCOPe 2.08: d2yeea_
  • Heterogens: SO4, 2EC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2yeeA (A:)
    mghhhhhhhhhhssghiddadkhmdqpmeeehvetfafqaeiaqlmsliintfysnkeif
    lrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadli
    nnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawes
    saggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfqgypitlfvek
    erdkevsddeae
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yeeA (A:)
    hvetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
    lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
    vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
    eyleerrikeivkkhsqfqgypitlfve