PDB entry 2y6d

View 2y6d on RCSB PDB site
Description: the discovery of mmp7 inhibitors exploiting a novel selectivity trigger
Class: hydrolase
Keywords: hydrolase
Deposited on 2011-01-20, released 2011-05-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-05-04, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.19745
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Matrilysin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09237 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.01: d2y6da_
  • Heterogens: CA, ZN, SO4, TQJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2y6dA (A:)
gyslfpnspkwtskvvtyrivsytrdlphitvdrlvskalnmwgkeiplhfrkvvwgtad
imigfargahgdsypfdgpgntlahafapgtglggdahfdederwtdgsslginflyaat
helghslgmghssdpnavmyptygngdpqnfklsqddikgiqklygkrsnsrkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2y6dA (A:)
gyslfpnspkwtskvvtyrivsytrdlphitvdrlvskalnmwgkeiplhfrkvvwgtad
imigfargahgdsypfdgpgntlahafapgtglggdahfdederwtdgsslginflyaat
helghslgmghssdpnavmyptynfklsqddikgiqklyg