PDB entry 2xz5

View 2xz5 on RCSB PDB site
Description: MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine
Class: receptor
Keywords: receptor, amidation, conformational flexibility, conotoxin, neurotoxinnicotinic, postsynaptic neurotoxin, receptor/toxin
Deposited on 2010-11-23, released 2010-12-08
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-02-05, with a file datestamp of 2014-01-31.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.1753
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (135)
    Domains in SCOPe 2.05: d2xz5a_
  • Chain 'B':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (135)
    Domains in SCOPe 2.05: d2xz5b_
  • Chain 'C':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (135)
    Domains in SCOPe 2.05: d2xz5c_
  • Chain 'D':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (135)
    Domains in SCOPe 2.05: d2xz5d_
  • Chain 'E':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (135)
    Domains in SCOPe 2.05: d2xz5e_
  • Heterogens: ACH, CL, PO4, MPD, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xz5A (A:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2xz5A (A:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerrag

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xz5B (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2xz5B (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerrag

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2xz5C (C:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2xz5C (C:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerrag

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2xz5D (D:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2xz5D (D:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerrag

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2xz5E (E:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2xz5E (E:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyceqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerrag