PDB entry 2xba

View 2xba on RCSB PDB site
Description: structure of human anaplastic lymphoma kinase in complex with pha-e429
Class: transferase
Keywords: ATP-binding, receptor, transferase
Deposited on 2010-04-08, released 2010-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.195
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ALK tyrosine kinase receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xbaa_
  • Heterogens: 571, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xbaA (A:)
gpnycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktl
pevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretr
prpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfg
mardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympyps
ksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdv
intalpieygplvee

    Sequence, based on observed residues (ATOM records): (download) 
    >2xbaA (A:)
nycfagktssisdlkevprknitlirglvyegqvsplqvavktlpevcseqdeldflmea
liiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqpsslamldllh
vardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardiyamlpvkwmpp
eafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpv
yrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieyg