PDB entry 2w9i

View 2w9i on RCSB PDB site
Description: AChE in complex with methylene blue
Class: hydrolase
Keywords: alzheimer's disease, cell junction, glycoprotein, gpi-anchor, hydrolase, membrane, muscle, nerve, neurotransmitter degradation, serine esterase, serine hydrolase, synapse
Deposited on 2009-01-25, released 2010-03-31
Made obsolete by 5e4t on 2016-03-30

The last revision prior to the SCOPe 2.06 freeze date was dated 2012-08-22, with a file datestamp of 2012-08-17.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: 0.202
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Torpedo californica [TaxId:7787]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2w9ia_
  • Heterogens: NAG, MBT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w9iA (A:)
mnllvtsslgvllhlvvlcqaddhsellvntksgkvmgtrvpvlsshisaflgipfaepp
vgnmrfrrpepkkpwsgvwnastypnncqqyvdeqfpgfsgsemwnpnremsedclylni
wvpsprpksttvmvwiygggfysgsstldvyngkylayteevvlvslsyrvgafgflalh
gsqeapgnvglldqrmalqwvhdniqffggdpktvtifgesaggasvgmhilspgsrdlf
rrailqsgspncpwasvsvaegrrravelgrnlncnlnsdeelihclrekkpqelidvew
nvlpfdsifrfsfvpvidgeffptslesmlnsgnfkktqillgvnkdegsffllygapgf
skdseskisredfmsgvklsvphandlgldavtlqytdwmddnngiknrdglddivgdhn
vicplmhfvnkytkfgngtylyffnhrasnlvwpewmgvihgyeiefvfglplvkelnyt
aeeealsrrimhywatfaktgnpnephsqeskwplfttkeqkfidlntepmkvhqrlrvq
mcvfwnqflpkllnatacdgelsssgtssskgiifyvlfsilylif

    Sequence, based on observed residues (ATOM records): (download) 
    >2w9iA (A:)
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
epskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat