PDB entry 2w6c

View 2w6c on RCSB PDB site
Description: ache in complex with a bis-(-)-nor-meptazinol derivative
Class: hydrolase
Keywords: catalytic triad, serine hydrolase, alzheimer's disease, cell membrane, cholinesterase, serine esterase, neurotransmitter degradation, membrane, hydrolase, alternative splicing, gpi-anchor, glycoprotein, cell junction
Deposited on 2008-12-18, released 2009-04-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: acetylcholinesterase
    Species: Torpedo californica [TaxId:7787]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2w6cx_
  • Heterogens: BM4, NAG, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2w6cX (X:)
mnllvtsslgvllhlvvlcqaddhsellvntksgkvmgtrvpvlsshisaflgipfaepp
vgnmrfrrpepkkpwsgvwnastypnncqqyvdeqfpgfsgsemwnpnremsedclylni
wvpsprpksttvmvwiygggfysgsstldvyngkylayteevvlvslsyrvgafgflalh
gsqeapgnvglldqrmalqwvhdniqffggdpktvtifgesaggasvgmhilspgsrdlf
rrailqsgspncpwasvsvaegrrravelgrnlncnlnsdeelihclrekkpqelidvew
nvlpfdsifrfsfvpvidgeffptslesmlnsgnfkktqillgvnkdegsffllygapgf
skdseskisredfmsgvklsvphandlgldavtlqytdwmddnngiknrdglddivgdhn
vicplmhfvnkytkfgngtylyffnhrasnlvwpewmgvihgyeiefvfglplvkelnyt
aeeealsrrimhywatfaktgnpnephsqeskwplfttkeqkfidlntepmkvhqrlrvq
mcvfwnqflpkllnatacdgelsssgtssskgiifyvlfsilylif

    Sequence, based on observed residues (ATOM records): (download) 
    >2w6cX (X:)
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
epskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat