PDB entry 2vd7

View 2vd7 on RCSB PDB site
Description: Crystal Structure of JMJD2A complexed with inhibitor Pyridine-2,4- dicarboxylic acid
Class: oxidoreductase
Keywords: oxidoreductase, phosphorylation, chromatin regulator, iron, nucleus, zinc-finger, dioxygenase, host-virus interaction, transcription regulation, transcription, metal-binding, histone demethylation inhibitor jmjc domain
Deposited on 2007-10-01, released 2007-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-28, with a file datestamp of 2018-03-23.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: JmjC domain-containing histone demethylation protein 3A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vd7a_
  • Chain 'B':
    Compound: JmjC domain-containing histone demethylation protein 3A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2vd7b_
  • Heterogens: NI, ZN, PD2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vd7A (A:)
mhhhhhhssgvdlgtenlyfqsmasesetlnpsarimtfyptmeefrnfsryiayiesqg
ahraglakvvppkewkprasyddiddlvipapiqqlvtgqsglftqyniqkkamtvrefr
kiansdkyctprysefeelerkywknltfnppiygadvngtlyekhvdewnigrlrtild
lvekesgitiegvntpylyfgmwktsfawhtedmdlysinylhfgepkswysvppehgkr
lerlakgffpgsaqsceaflrhkmtlisplmlkkygipfdkvtqeagefmitfpygyhag
fnhgfncaestnfatrrwieygkqavlcscrkdmvkismdvfvrkfqperyklwkagkdn
tvidhtlptpeaaeflkesel

    Sequence, based on observed residues (ATOM records): (download) 
    >2vd7A (A:)
etlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddl
vipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknl
tfnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsf
awhtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtli
splmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavl
cscrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaeflk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vd7B (B:)
mhhhhhhssgvdlgtenlyfqsmasesetlnpsarimtfyptmeefrnfsryiayiesqg
ahraglakvvppkewkprasyddiddlvipapiqqlvtgqsglftqyniqkkamtvrefr
kiansdkyctprysefeelerkywknltfnppiygadvngtlyekhvdewnigrlrtild
lvekesgitiegvntpylyfgmwktsfawhtedmdlysinylhfgepkswysvppehgkr
lerlakgffpgsaqsceaflrhkmtlisplmlkkygipfdkvtqeagefmitfpygyhag
fnhgfncaestnfatrrwieygkqavlcscrkdmvkismdvfvrkfqperyklwkagkdn
tvidhtlptpeaaeflkesel

    Sequence, based on observed residues (ATOM records): (download) 
    >2vd7B (B:)
tlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlv
ipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknlt
fnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfa
whtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlis
plmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlc
scrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaeflk