PDB entry 2uxz

View 2uxz on RCSB PDB site
Description: two-carbon-elongated hiv-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic
Class: hydrolase
Keywords: hiv-1, protease, hydrolase, inhibitor, aspartyl protease
Deposited on 2007-04-02, released 2008-05-20
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.202
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hiv-1 protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366
  Domains in SCOPe 2.02: d2uxza_
• Chain 'B':
  Compound: hiv-1 protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366 (0-98)
  Domains in SCOPe 2.02: d2uxzb_
• Heterogens: HI1, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2uxzA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2uxzB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf