PDB entry 2rhb

View 2rhb on RCSB PDB site
Description: Crystal structure of Nsp15-H234A mutant- Hexamer in asymmetric unit
Class: viral protein
Keywords: endoribonuclease, sars, hexamer, RNA, nsp, viral protein
Deposited on 2007-10-08, released 2007-11-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridylate-specific endoribonuclease
    Species: SARS coronavirus [TaxId:227859]
    Gene: Nsp15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (7-End)
      • expression tag (6)
      • engineered (240)
    Domains in SCOPe 2.07: d2rhba1, d2rhba2, d2rhba3
  • Chain 'B':
    Compound: Uridylate-specific endoribonuclease
    Species: SARS coronavirus [TaxId:227859]
    Gene: Nsp15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (7-End)
      • expression tag (5-6)
      • engineered (240)
    Domains in SCOPe 2.07: d2rhbb1, d2rhbb2, d2rhbb3
  • Chain 'C':
    Compound: Uridylate-specific endoribonuclease
    Species: SARS coronavirus [TaxId:227859]
    Gene: Nsp15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (7-End)
      • expression tag (6)
      • engineered (240)
    Domains in SCOPe 2.07: d2rhbc1, d2rhbc2, d2rhbc3
  • Chain 'D':
    Compound: Uridylate-specific endoribonuclease
    Species: SARS coronavirus [TaxId:227859]
    Gene: Nsp15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (7-End)
      • expression tag (5-6)
      • engineered (240)
    Domains in SCOPe 2.07: d2rhbd1, d2rhbd2, d2rhbd3
  • Chain 'E':
    Compound: Uridylate-specific endoribonuclease
    Species: SARS coronavirus [TaxId:227859]
    Gene: Nsp15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (7-End)
      • expression tag (5-6)
      • engineered (240)
    Domains in SCOPe 2.07: d2rhbe1, d2rhbe2, d2rhbe3
  • Chain 'F':
    Compound: Uridylate-specific endoribonuclease
    Species: SARS coronavirus [TaxId:227859]
    Gene: Nsp15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (7-End)
      • engineered (240)
    Domains in SCOPe 2.07: d2rhbf1, d2rhbf2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2rhbA (A:)
hhhhhhmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnv
afelwakrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkpte
sacssltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvk
tqfnyfkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafe
aivygdfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcs
vidlllddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhbA (A:)
mslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelwa
krnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacssl
tvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfnyf
kkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafeaivygd
fshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcsvidlll
ddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2rhbB (B:)
hhhhhhmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnv
afelwakrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkpte
sacssltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvk
tqfnyfkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafe
aivygdfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcs
vidlllddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhbB (B:)
hmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelw
akrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacss
ltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfny
fkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafeaivyg
dfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2rhbC (C:)
hhhhhhmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnv
afelwakrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkpte
sacssltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvk
tqfnyfkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafe
aivygdfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcs
vidlllddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhbC (C:)
mslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelwa
krnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacssl
tvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfnyf
kkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafeaivygd
fshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcsvidlll
ddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2rhbD (D:)
hhhhhhmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnv
afelwakrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkpte
sacssltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvk
tqfnyfkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafe
aivygdfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcs
vidlllddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhbD (D:)
hmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelw
akrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacss
ltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfny
fkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafeaivyg
dfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2rhbE (E:)
hhhhhhmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnv
afelwakrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkpte
sacssltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvk
tqfnyfkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafe
aivygdfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcs
vidlllddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhbE (E:)
hmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelw
akrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacss
ltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfny
fkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafeaivyg
dfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2rhbF (F:)
hhhhhhmslenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnv
afelwakrnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkpte
sacssltvlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvk
tqfnyfkkvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafe
aivygdfshgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcs
vidlllddfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >2rhbF (F:)
slenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelwak
rnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacsslt
vlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfnyfk
kvdgiiqqlpetyftqsrdledfkprsqmetdflelamdefiqryklegyafeaivygdf
shgqlgglhlmiglakrsqdsplkledfipmdstvknyfitdaqtgsskcvcsvidllld
dfveiiksqdlsviskvvkvtidyaeisfmlwckdghvetfypk