PDB entry 2r9s

View 2r9s on RCSB PDB site
Description: c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor
Class: signaling protein, transferase
Keywords: jnk3, SIGNALING PROTEIN, TRANSFERASE
Deposited on 2007-09-13, released 2007-10-16
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.209
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P53779 (0-355)
      • modified residue (108)
      • modified residue (129)
      • modified residue (155)
    Domains in SCOPe 2.02: d2r9sa_
  • Chain 'B':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P53779 (0-355)
      • modified residue (108)
      • modified residue (129)
      • modified residue (155)
    Domains in SCOPe 2.02: d2r9sb_
  • Heterogens: 255, UNX, TFA, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r9sA (A:)
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyvv
tryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpe
fmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpa
krisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmns

    Sequence, based on observed residues (ATOM records): (download) 
    >2r9sA (A:)
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglaryyrapevilgmgy
kenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyven
rpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyin
vwydkqlderehtieewkeliykevmns

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2r9sB (B:)
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyvv
tryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpe
fmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpa
krisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmns

    Sequence, based on observed residues (ATOM records): (download) 
    >2r9sB (B:)
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglaryyrapevilgmgy
kenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyven
rpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyin
vwydkqlderehtieewkeliykevmns