PDB entry 2qfy

View 2qfy on RCSB PDB site
Description: Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with a-ketoglutarate
Class: Oxidoreductase
Keywords: Rossmann fold, Oxidoreductase
Deposited on 2007-06-28, released 2008-07-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.206
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qfya_
  • Chain 'B':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qfyb_
  • Chain 'C':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qfyc_
  • Chain 'D':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qfyd_
  • Chain 'E':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qfye_
  • Chain 'F':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qfyf_
  • Heterogens: AKG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qfyA (A:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfyA (A:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiksi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qfyB (B:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfyB (B:)
afskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqd
aaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipripr
lvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgv
amamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqyksk
feqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtp
dgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfani
lesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qfyC (C:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfyC (C:)
afskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqd
aaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipripr
lvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgv
amamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqyksk
feqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtp
dgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfani
lesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qfyD (D:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfyD (D:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiksi

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2qfyE (E:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfyE (E:)
afskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqd
aaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipripr
lvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgv
amamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqyksk
feqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtp
dgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfani
lesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2qfyF (F:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfyF (F:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiksi