PDB entry 2qe2

View 2qe2 on RCSB PDB site
Description: Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor
Class: transferase
Keywords: transferase
Deposited on 2007-06-22, released 2007-10-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.279
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-directed RNA polymerase
    Species: Hepatitis C virus subtype 1b [TaxId:31647]
    Gene: NS5B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2qe2a_
  • Chain 'B':
    Compound: RNA-directed RNA polymerase
    Species: Hepatitis C virus subtype 1b [TaxId:31647]
    Gene: NS5B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2qe2b_
  • Heterogens: 452

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qe2A (A:)
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasqldlsgwfvagysggdiyhslsrarprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2qe2A (A:)
llrhhnmvyattsrsaglrqkkvtfdrlqvlddhyrdvlkemkakastvkakllsveeac
kltpphsafgygakdvrnlsskavnhihsvwkdlledpidttimaknevfcvqpeggrkp
arlivfpdlgvrvcekmalydvvstlpqvvmgssygfqyspgqrveflvntwkskknpmg
fsydtrcfdstvtendirveesiyqccdlapearqaikslterlyiggpltnskgqncgy
rrcrasgvlttscgntltcylkasaacraaklqdctmlvngddlvvicesagtqedaasl
rvfteamtryppgdppqpeydlelitscssnvsvahdasgkrvyyltrdpttplaraawe
tarhtpvnswlgniimyaptlwarmilmthffsillaqeqlekaldcqiygacysiepld
lpqiierlhglsafslhsyspgeinrvasclrklgvpplrvwrhrarsvrarllsqggra
atcgkylfnwavktklkltpipaaslsgwfvagysggdiyh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qe2B (B:)
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasqldlsgwfvagysggdiyhslsrarprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2qe2B (B:)
rhhnmvyattsrsaglrqkkvtfdrlqvlddhyrdvlkemkakastvkakllsveeackl
tpphsakskfgygakdvrnlsskavnhihsvwkdlledpidttimaknevfcvqpekggr
kparlivfpdlgvrvcekmalydvvstlpqvvmgssygfqyspgqrveflvntwkskknp
mgfsydtrcfdstvtendirveesiyqccdlapearqaikslterlyiggpltnskgqnc
gyrrcrasgvlttscgntltcylkasaacraaklqdctmlvngddlvvicesagtqedaa
slrvfteamtryppgdppqpeydlelitscssnvsvahdasgkrvyyltrdpttplaraa
wetarhtpvnswlgniimyaptlwarmilmthffsillaqeqlekaldcqiygacysiep
ldlpqiierlhglsafslhsyspgeinrvasclrklgvpplrvwrhrarsvrarllsqgg
raatcgkylfnwavktklkltpipaaslsgwfvagysggdiyh