PDB entry 2qdc

View 2qdc on RCSB PDB site
Description: Crystal structure of the HePTP catalytic domain D236A mutant
Class: hydrolase
Keywords: HePTP, human hematopoietic tyrosine phosphatase catalytic domain mutant, LC-PTP, PTPN7, HYDROLASE
Deposited on 2007-06-20, released 2008-06-24
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.164
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 7
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35236
      • engineered (205)
    Domains in SCOPe 2.02: d2qdca_
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qdcA (A:)
mgsdkihhhhhhmntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvsp
edldipghaskdryktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgp
mpntvsdfwemvwqeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpey
tvrqltiqyqeerrsvkhilfsawpahqtpesagpllrlvaeveespetaahpgpivvhc
sagigrtgcfiatrigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalya
gqlpeepsp

    Sequence, based on observed residues (ATOM records): (download) 
    >2qdcA (A:)
tprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdry
ktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvwq
eevslivmltqlvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeerrsvkhilf
sawpahqtpesagpllrlvaeveespetaahpgpivvhcsagigrtgcfiatrigcqqlk
argevdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpe