PDB entry 2p3o

View 2p3o on RCSB PDB site
Description: Crystal Structure of Dengue Methyltransferase in Complex with 7MeGpppA and S-Adenosyl-L-homocysteine
Class: viral protein,transferase
Keywords: VIZIER; Viral Enzymes Involved in Replication; Dengue virus methyltransferase; Structural Genomics; Marseilles Structural Genomics Program @ AFMB; MSGP, VIRAL PROTEIN,TRANSFERASE
Deposited on 2007-03-09, released 2007-08-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.76 Å
R-factor: 0.198
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: type II methyltransferase
    Species: Dengue virus 2 [TaxId:11060]
    Gene: NSP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WLZ8
      • see remark 999 (78)
      • see remark 999 (147)
      • see remark 999 (181)
      • see remark 999 (188)
      • see remark 999 (196)
      • see remark 999 (209)
    Domains in SCOPe 2.08: d2p3oa_
  • Heterogens: SO4, SAH, CIT, GTA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2p3oA (A:)
mrgshhhhhhgsnigetlgekwksrlnalgksefqiykksgiqevdrtlakegikrgetd
hhavsrgsaklrwfvernlvtpegkvvdlgcgrggwsyycgglknvrevkgltkggpghe
epipmstygwnlvrlqsgvdvffippercdtllcdigesspnptveagrtlrvlnlvenw
lsnntqfcvkvlnpymssviekmealqrkhggalvrnplsrnsthemywvsnasgnivss
vnmisrmlinrftmrhkkatyepdvdlgsgtrnigiesetpnldiigkriekikqehets
whydq

    Sequence, based on observed residues (ATOM records): (download) 
    >2p3oA (A:)
etlgekwksrlnalgksefqiykksgiqevdrtlakegikrgetdhhavsrgsaklrwfv
ernlvtpegkvvdlgcgrggwsyycgglknvrevkgltkggpgheepipmstygwnlvrl
qsgvdvffippercdtllcdigesspnptveagrtlrvlnlvenwlsnntqfcvkvlnpy
mssviekmealqrkhggalvrnplsrnsthemywvsnasgnivssvnmisrmlinrftmr
hkkatyepdvdlgsgtrn