PDB entry 2gdz

View 2gdz on RCSB PDB site
Description: Crystal structure of 15-hydroxyprostaglandin dehydrogenase type1, complexed with NAD+
Class: oxidoreductase
Keywords: hydroxyprostaglandin, dehydrogenase, Structural Genomics, SHORT-CHAIN DEHYDROGENASE/REDUCTASE, INFLAMMATION, Structural Genomics Consortium, SGC, OXIDOREDUCTASE
Deposited on 2006-03-17, released 2006-04-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.177
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15428 (4-257)
      • expression tag (1-3)
      • expression tag (258-266)
    Domains in SCOPe 2.06: d2gdza1, d2gdza2, d2gdza3
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gdzA (A:)
mahmvngkvalvtgaaqgigrafaealllkgakvalvdwnleagvqckaalheqfepqkt
lfiqcdvadqqqlrdtfrkvvdhfgrldilvnnagvnneknwektlqinlvsvisgtylg
ldymskqnggeggiiinmsslaglmpvaqqpvycaskhgivgftrsaalaanlmnsgvrl
naicpgfvntailesiekeenmgqyieykdhikdmikyygildpplianglitlieddal
ngaimkittskgihfqdygskenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2gdzA (A:)
ahmvngkvalvtgaaqgigrafaealllkgakvalvdwnleagvqckaalheqfepqktl
fiqcdvadqqqlrdtfrkvvdhfgrldilvnnagvnneknwektlqinlvsvisgtylgl
dymskqnggeggiiinmsslaglmpvaqqpvycaskhgivgftrsaalaanlmnsgvrln
aicpgfvntailesiekeenmgqyieykdhikdmikyygildpplianglitlieddaln
gaimkittskgihfqdygskenlyfq