PDB entry 2g8a

View 2g8a on RCSB PDB site
Description: Lactobacillus casei Y261M in complex with substrate, dUMP
Class: transferase
Keywords: beta sheet, alpha-beta protein, dUMP complex, active site mutation, methyltransferase, TRANSFERASE
Deposited on 2006-03-02, released 2006-03-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.203
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Lactobacillus casei [TaxId:1582]
    Gene: thyA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00469 (0-315)
      • engineered (260)
    Domains in SCOPe 2.06: d2g8aa_
  • Heterogens: UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2g8aA (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlv
ahecglevgefihtfgdahlmvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
llnydpypaikapvav