PDB entry 2g0h
View 2g0h on RCSB PDB site
Description: Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities
Class: transcription activator
Keywords: ppar, transcription activator
Deposited on
2006-02-13, released
2006-05-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.238
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2g0ha_ - Chain 'B':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2g0hb_ - Heterogens: SP3, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2g0hA (A:)
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2g0hB (B:)
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly