PDB entry 2fyb

View 2fyb on RCSB PDB site
Description: Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in complex with Mn and UDP-galactose in open conformation
Class: transferase
Keywords: M339H mutant, complex with UDP-galactose and Mn, open conformation, TRANSFERASE
Deposited on 2006-02-07, released 2006-03-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.178
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • cloning artifact (9-13)
      • engineered (225-226)
      • engineered (228)
    Domains in SCOPe 2.06: d2fyba1, d2fyba2
  • Heterogens: MN, UDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fybA (A:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >2fybA (A:)
grgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvai
iipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdyd
ytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqflti
ngfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhspnpqrfdriahtketm
lsdglnsltyqvldvqryplytqitvdigtps