PDB entry 2fwb

View 2fwb on RCSB PDB site
Description: Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H89F from the acidophilic bacterium Acetobacter aceti, at pH 8
Class: Lyase
Keywords: acidophile, PurE, purine biosynthesis, Lyase
Deposited on 2006-02-01, released 2006-06-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.178
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N5-carboxyaminoimidazole ribonucleotide mutase
    Species: Acetobacter aceti [TaxId:435]
    Gene: purE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2QJL3
      • engineered (89)
    Domains in SCOPe 2.08: d2fwba_
  • Chain 'B':
    Compound: N5-carboxyaminoimidazole ribonucleotide mutase
    Species: Acetobacter aceti [TaxId:435]
    Gene: purE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2QJL3
      • engineered (89)
    Domains in SCOPe 2.08: d2fwbb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fwbA (A:)
mmsetaplpsassaledkaasapvvgiimgsqsdwetmrhadallteleiphetlivsah
rtpdrladyartaaerglnviiagaggaaflpgmcaawtrlpvlgvpvesralkgmdsll
sivqmpggvpvgtlaigasgaknaallaasilalynpalaarletwralqtasvpnspit
edk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fwbA (A:)
sapvvgiimgsqsdwetmrhadallteleiphetlivsahrtpdrladyartaaerglnv
iiagaggaaflpgmcaawtrlpvlgvpvesralkgmdsllsivqmpggvpvgtlaigasg
aknaallaasilalynpalaarletwralqtasvpnspi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2fwbB (B:)
mmsetaplpsassaledkaasapvvgiimgsqsdwetmrhadallteleiphetlivsah
rtpdrladyartaaerglnviiagaggaaflpgmcaawtrlpvlgvpvesralkgmdsll
sivqmpggvpvgtlaigasgaknaallaasilalynpalaarletwralqtasvpnspit
edk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fwbB (B:)
sapvvgiimgsqsdwetmrhadallteleiphetlivsahrtpdrladyartaaerglnv
iiagaggaaflpgmcaawtrlpvlgvpvesralkgmdsllsivqmpggvpvgtlaigasg
aknaallaasilalynpalaarletwralqtasvpnspited