PDB entry 2flp

View 2flp on RCSB PDB site
Description: Binary complex of the catalytic core of human DNA polymerase iota with DNA (template G)
Class: replication/DNA
Keywords: DNA polymerase, lesion bypass, Y-family, binary complex, template G, REPLICATION-DNA COMPLEX
Deposited on 2006-01-06, released 2006-12-05
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.233
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase iota
    Species: Homo sapiens [TaxId:9606]
    Gene: POLI, RAD30B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2flpa1, d2flpa2
  • Chain 'P':
    Compound: DNA primer strand
  • Chain 'T':
    Compound: DNA template strand
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2flpA (A:)
meladvgaaassqgvhdqvlptpnassrvivhvdldcfyaqvemisnpelkdkplgvqqk
ylvvtcnyearklgvkklmnvrdakekcpqlvlvngedltryremsykvtelleefspvv
erlgfdenfvdltemvekrlqqlqsdelsavtvsghvynnqsinlldvlhirllvgsqia
aemreamynqlgltgcagvasnkllaklvsgvfkpnqqtvllpescqhlihslnhikeip
gigyktakclealginsvrdlqtfspkilekelgisvaqriqklsfgednspvilsgppq
sfseedsfkkcsseveaknkieellasllnrvcqdgrkphtvrliirryssekhygresr
qcpipshviqklgtgnydvmtpmvdilmklfrnmvnvkmpfhltllsvcfcnlkalntak

    Sequence, based on observed residues (ATOM records): (download) 
    >2flpA (A:)
ssrvivhvdldcfyaqvemisnpelkdkplgvqqkylvvtcnyearklgvkklmnvrdak
ekcpqlvlvngedltryremsykvtelleefspvverlgfdenfvdltemvekrlqqlqs
delsavtvsghvynnqsinlldvlhirllvgsqiaaemreamynqlgltgcagvasnkll
aklvsgvfkpnqqtvllpescqhlihslnhikeipgigyktakclealginsvrdlqtfs
pkilekelgisvaqriqklsfgednspvilsgppqsfseedsfkkcsseveaknkieell
asllnrvcqdgrkphtvrliirryygresrqcpipshviqvmtpmvdilmklfrnmtlls
vcfcnlk

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.