PDB entry 2fdd

View 2fdd on RCSB PDB site
Description: Crystal structure of HIV protease D545701 bound with GW0385
Class: hydrolase
Keywords: HIV protease, inhibitor, HYDROLASE
Deposited on 2005-12-13, released 2006-02-21
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: 0.217
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gag-Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • GB POL_HV1PV (1-99)
      • engineered (10)
      • engineered (19-20)
      • engineered (35-37)
      • engineered (46)
      • engineered (50)
      • engineered (54)
      • engineered (62-63)
      • engineered (71)
      • engineered (82)
      • engineered (90)
    Domains in SCOPe 2.01: d2fdda_
  • Chain 'B':
    Compound: Gag-Pol polyprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • GB POL_HV1PV (1-99)
      • engineered (10)
      • engineered (19-20)
      • engineered (35-37)
      • engineered (46)
      • engineered (50)
      • engineered (54)
      • engineered (62-63)
      • engineered (71)
      • engineered (82)
      • engineered (90)
    Domains in SCOPe 2.01: d2fddb_
  • Heterogens: 385, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fddA (A:)
mpqitlwqrpivtikiggqqrealldtgaddtvledinlpgrwkpkiiggvggfvkvrqy
dqvpieicghkvigtvlvgptpaniigrnlmtqigctlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >2fddA (A:)
pqitlwqrpivtikiggqqrealldtgaddtvledinlpgrwkpkiiggvggfvkvrqyd
qvpieicghkvigtvlvgptpaniigrnlmtqigctlnf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2fddB (B:)
mpqitlwqrpivtikiggqqrealldtgaddtvledinlpgrwkpkiiggvggfvkvrqy
dqvpieicghkvigtvlvgptpaniigrnlmtqigctlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >2fddB (B:)
pqitlwqrpivtikiggqqrealldtgaddtvledinlpgrwkpkiiggvggfvkvrqyd
qvpieicghkvigtvlvgptpaniigrnlmtqigctlnf