PDB entry 2dsr

View 2dsr on RCSB PDB site
Description: Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins
Class: protein binding/hormone/growth factor
Keywords: IGF, IGFBP, Insulin, PROTEIN BINDING/HORMONE/GROWTH FACTOR COMPLEX
Deposited on 2006-07-05, released 2006-08-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.202
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Insulin-like growth factor-binding protein 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2dsrb_
  • Chain 'G':
    Compound: Insulin-like growth factor-binding protein 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2dsrg1
  • Chain 'I':
    Compound: Insulin-like growth factor IB
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2dsri_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2dsrB (B:)
aihcppcseeklarcrppvgceelvrepgcgccatcalglgmpcgvytprcgsglrcypp
rgvekplhtlmhgqgvcmel

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2dsrG (G:)
gscqselhralerlaasqsrthedlyiipipncdrngnfhpkqchpaldgqrgkcwcvdr
ktgvklpgglepkgeldchqla

    Sequence, based on observed residues (ATOM records): (download) 
    >2dsrG (G:)
gscqselhralerlaasqsrthedlyiipipncdrngnfhpkqchpaldgqrgkcwcvdr
ktgvklpgglepkgeldch

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2dsrI (I:)
gpetlcgaelvdalqfvcgdrgfyfnkptgygsssrrapqtgivdeccfrscdlrrlemy
caplkpaksa

    Sequence, based on observed residues (ATOM records): (download) 
    >2dsrI (I:)
petlcgaelvdalqfvcgdrgfyfnkptgygssapqtgivdeccfrscdlrrlemycapl