PDB entry 2bzn

View 2bzn on RCSB PDB site
Description: crystal structure of human guanosine monophosphate reductase 2 gmpr2 in complex with imp
Class: oxidoreductase
Keywords: tim barrel, oxidoreductase
Deposited on 2005-08-19, released 2005-09-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-30, with a file datestamp of 2011-11-25.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.161
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bzna1, d2bzna2
  • Chain 'B':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bznb1, d2bznb2
  • Chain 'C':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bznc1, d2bznc2
  • Chain 'D':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bznd1, d2bznd2
  • Chain 'E':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bzne1, d2bzne2
  • Chain 'F':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bznf1, d2bznf2
  • Chain 'G':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bzng1, d2bzng2
  • Chain 'H':
    Compound: GMP reductase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BZN (Start-18)
    • Uniprot Q9P2T1 (19-End)
    Domains in SCOPe 2.07: d2bznh1, d2bznh2
  • Heterogens: IMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bznA (A:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznA (A:)
sldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlc
kfslftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicl
dvangysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvctt
rkktgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlagh
sesggelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstc
tyvgaaklkelsrrttfirv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bznB (B:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznB (B:)
sldfkdvllrpkrstlevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlckfsl
ftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicldvan
gysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvcttrkkt
gvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlaghsesg
gelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstctyvg
aaklkelsrrttfirvt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2bznC (C:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznC (C:)
sldfkdvllrpkrstlkevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlckfs
lftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicldva
ngysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvcttrkk
tgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlaghses
ggelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstctyv
gaaklkelsrrttfirv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2bznD (D:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznD (D:)
sldfkdvllrpkrstlevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlckfsl
ftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicldvan
gysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvcttrkkt
gvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlaghsesg
gelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstctyvg
aaklkelsrrttfirv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2bznE (E:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznE (E:)
sldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlc
kfslftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicl
dvangysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvctt
rkktgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlagh
sesggelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstc
tyvgaaklkelsrrttfirv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2bznF (F:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznF (F:)
sldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlc
kfslftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicl
dvangysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvctt
rkktgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlagh
sesggelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstc
tyvgaaklkelsrrttfirvt

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2bznG (G:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznG (G:)
sldfkdvllrpkrstlevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlckfsl
ftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicldvan
gysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvcttrkkt
gvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlaghsesg
gelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstctyvg
aaklkelsrrttfirvt

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2bznH (H:)
mgsshhhhhhssglvprgsldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpi
iaanmdtvgtfemakvlckfslftavhkhyslvqwqefagqnpdclehlaassgtgssdf
eqleqileaipqvkyicldvangysehfvefvkdvrkrfpqhtimagnvvtgemveelil
sgadiikvgigpgsvcttrkktgvgypqlsavmecadaahglkghiisdggcscpgdvak
afgagadfvmlggmlaghsesggelierdgkkyklfygmssemamkkyaggvaeyraseg
ktvevpfkgdvehtirdilggirstctyvgaaklkelsrrttfirvtqqvn

    Sequence, based on observed residues (ATOM records): (download) 
    >2bznH (H:)
sldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlc
kfslftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicl
dvangysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvctt
rkktgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlagh
sesggelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstc
tyvgaaklkelsrrttfirv