PDB entry 2b7z

View 2b7z on RCSB PDB site
Description: Structure of HIV-1 protease mutant bound to indinavir
Class: viral protein
Keywords: HIV-1, protease, indinavir, drug resistance, active site mutations, non-active site mutations,VIRAL PROTEIN, VIRAL PROTEIN
Deposited on 2005-10-05, released 2006-11-14
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.216
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (19)
    • engineered (31-32)
    • engineered (35)
    • engineered (45)
    • engineered (62)
    • engineered (70)
    • engineered (81)
    • engineered (83)
    • engineered (89)
  Domains in SCOPe 2.01: d2b7za_
• Chain 'B':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (19)
    • engineered (31-32)
    • engineered (35)
    • engineered (45)
    • engineered (62)
    • engineered (70)
    • engineered (81)
    • engineered (83)
    • engineered (89)
  Domains in SCOPe 2.01: d2b7zb_
• Heterogens: MK1, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2b7zA (A:)
  pqitlwqrplvtikiggqlrealldtgaddtifeeislpgrwkpkiiggiggfikvrqyd
  qipieicghkvigtvlvgptpanvigrnlmtqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2b7zB (B:)
  pqitlwqrplvtikiggqlrealldtgaddtifeeislpgrwkpkiiggiggfikvrqyd
  qipieicghkvigtvlvgptpanvigrnlmtqigctlnf