PDB entry 1zsl
View 1zsl on RCSB PDB site
Description: Factor XI complexed with a pyrimidinone inhibitor
Class: hydrolase
Keywords: serine protease, coagulation, covalent complex, HYDROLASE
Deposited on
2005-05-24, released
2006-05-09
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.239
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Coagulation factor XI
Species: Homo sapiens [TaxId:9606]
Gene: F11
Database cross-references and differences (RAF-indexed):
- Uniprot P03951 (0-End)
- engineered (67)
- engineered (112)
Domains in SCOPe 2.01: d1zsla_ - Heterogens: 624, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1zslA (A:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseiaedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpislpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqav
Sequence, based on observed residues (ATOM records): (download)
>1zslA (A:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseiaedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpislpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqa