PDB entry 1t7d
View 1t7d on RCSB PDB site
Description: Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Class: hydrolase/antibiotic
Keywords: signal peptidase, ser/lys dyad, hydrolase, lipopeptide, antibiotic, biaryl bridge, hydrolase-antibiotic complex
Deposited on
2004-05-09, released
2004-07-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-27, with a file datestamp of
2011-07-22.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: 0.23
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Signal peptidase I
Species: Escherichia coli [TaxId:562]
Gene: LEPB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1t7da_ - Chain 'B':
Compound: Signal peptidase I
Species: Escherichia coli [TaxId:562]
Gene: LEPB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1t7db_ - Chain 'C':
Compound: arylomycin a2
Species: STREPTOMYCES TU [TaxId:1931]
Database cross-references and differences (RAF-indexed):
- NOR NOR01115 (0-5)
- NOR NOR00115 (0-5)
- Chain 'D':
Compound: arylomycin a2
Species: STREPTOMYCES TU [TaxId:1931]
Database cross-references and differences (RAF-indexed):
- NOR NOR01115 (0-5)
- NOR NOR00115 (0-5)
- Heterogens: M12, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1t7dA (A:)
mivrsfiyepfqipsgsmmptlligdfilvekfaygikdpiyqktlietghpkrgdivvf
kypedpkldyikravglpgdkvtydpvskeltiqpgcssgqacenalpvtysnvepsdfv
qtfsrrnggeatsgffevpknetkengirlserketlgdvthriltvpiaqdqvgmyyqq
pgqqlatwivppgqyfmmgdnrdnsadsrywgfvpeanlvgrataiwmsfdkqegewptg
lrlsriggih
Sequence, based on observed residues (ATOM records): (download)
>1t7dA (A:)
iyepfqipsgsmmptlligdfilvekfhpkrgdivvfkypedpkldyikravglpgdkvt
ydpvskeltiqpgcnalpvtysnvepsdfvqtfsrreatsgffevpknetkengirlser
ketlgdvthriltvpiaqdqvgmyyqqpgqqlatwivppgqyfmmgdnrdnsadsrywgf
vpeanlvgrataiwmsfdlrlsriggih
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1t7dB (B:)
mivrsfiyepfqipsgsmmptlligdfilvekfaygikdpiyqktlietghpkrgdivvf
kypedpkldyikravglpgdkvtydpvskeltiqpgcssgqacenalpvtysnvepsdfv
qtfsrrnggeatsgffevpknetkengirlserketlgdvthriltvpiaqdqvgmyyqq
pgqqlatwivppgqyfmmgdnrdnsadsrywgfvpeanlvgrataiwmsfdkqegewptg
lrlsriggih
Sequence, based on observed residues (ATOM records): (download)
>1t7dB (B:)
iyepfqipsgsmmptlligdfilvekfaetghpkrgdivvfkypedpkldyikravglpg
dkvtydpvskeltiqpgcssgqacenalpvtysnvepsdfvqtfssgffevpknetkeng
irlserketlgdvthriltvpiaqdqvgmyyqqpgqqlatwivppgqyfmmgdnrdnsad
srywgfvpeanlvgrataiwmsfdkqegewptglrlsriggih
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.