PDB entry 1svc

View 1svc on RCSB PDB site
Description: nfkb p50 homodimer bound to DNA
Class: transcription/DNA
Keywords: DNA-binding, transcription regulation, activator, nuclear protein, phosphorylation, repeat, DNA, transcription/DNA complex
Deposited on 1995-11-27, released 1996-06-10
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.225
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: DNA (5'-d(*ap*gp*ap*tp*gp*gp*gp*gp*ap*ap*tp*cp*cp*cp*cp*tp*a p*gp*a)-3')
  • Chain 'P':
    Compound: protein (nuclear factor kappa-b (nf-kb))
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19838
      • engineered (60)
    Domains in SCOPe 2.02: d1svcp1, d1svcp2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1svcP (P:)
aeddpylgrpeqmfhldpslthtifnpevfqpqmalptadgpylqileqpkqrgfrfryv
aegpshgglpgasseknkksypqvkicnyvgpakvivqlvtngknihlhahslvgkhced
gictvtagpkdmvvgfanlgilhvtkkkvfetlearmteacirgynpgllvhpdlaylqa
egggdrqlgdrekelirqaalqqtkemdlsvvrlmftaflpdstgsftrrlepvvsdaiy
dskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdf
sptdvhrqfaivfktpkykdinitkpasvfvqlrrksdletsepkpflyypeikdkeevq
rkrqk

    Sequence, based on observed residues (ATOM records): (download) 
    >1svcP (P:)
pylqileqpkqrgfrfryvaegpshgglpgasseknkksypqvkicnyvgpakvivqlvt
ngknihlhahslvgkhcedgictvtagpkdmvvgfanlgilhvtkkkvfetlearmteac
irgynpgllvhpdlaylqaegggdrqlgdrekelirqaalqqtkemdlsvvrlmftaflp
dstgsftrrlepvvsdaiydskapnasnlkivrmdrtagcvtggeeiyllcdkvqkddiq
irfyeeeenggvwegfgdfsptdvhrqfaivfktpkykdinitkpasvfvqlrrksdlet
sepkpflyype