PDB entry 1sgu

View 1sgu on RCSB PDB site
Description: Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease
Class: hydrolase
Keywords: active site mutations, non-active site mutations, indinavir, hiv-1 protease, hydrolase
Deposited on 2004-02-24, released 2004-10-05
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.22
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Pol polyprotein
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (19)
    • engineered (31-32)
    • engineered (35)
    • engineered (53)
    • engineered (62)
    • engineered (70)
    • engineered (81)
    • engineered (83)
    • engineered (89)
  Domains in SCOPe 2.02: d1sgua_
• Chain 'B':
  Compound: Pol polyprotein
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (19)
    • engineered (31-32)
    • engineered (35)
    • engineered (53)
    • engineered (62)
    • engineered (70)
    • engineered (81)
    • engineered (83)
    • engineered (89)
  Domains in SCOPe 2.02: d1sgub_
• Heterogens: MK1, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1sguA (A:)
  pqitlwqrplvtikiggqlrealldtgaddtifeeislpgrwkpkmiggiggfvkvrqyd
  qipieicghkvigtvlvgptpanvigrnlmtqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1sguB (B:)
  pqitlwqrplvtikiggqlrealldtgaddtifeeislpgrwkpkmiggiggfvkvrqyd
  qipieicghkvigtvlvgptpanvigrnlmtqigctlnf