PDB entry 1ra0

View 1ra0 on RCSB PDB site
Description: Bacterial cytosine deaminase D314G mutant bound to 5-fluoro-4-(S)-hydroxy-3,4-dihydropyrimidine.
Class: hydrolase
Keywords: CYTOSINE DEAMINASE, ALPHA-BETA BARREL, HEXAMER, CONFORMATIONAL CHANGE, D314G mutant, HYDROLASE
Deposited on 2003-10-31, released 2004-10-05
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.12 Å
R-factor: 0.168
AEROSPACI score: 0.88 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytosine deaminase
    Species: Escherichia coli [TaxId:562]
    Gene: CODA, B0337
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25524 (Start-429)
      • engineered (317)
    Domains in SCOPe 2.01: d1ra0a1, d1ra0a2
  • Heterogens: FE, FPY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ra0A (A:)
gssmannalqtiinarlpgeeglwqihlqdgkisaidaqsgvmpitensldaeqglvipp
fvephihldttqtagqpnwnqsgtlfegierwaerkallthddvkqrawqtlkwqiangi
qhvrthvdvsdatltalkamlevkqevapwidlqivafpqegilsypngealleealrlg
advvgaiphfeftreygveslhktfalaqkydrlidvhcdeiddeqsrfvetvaalahhe
gmgarvtashttamhsyngaytsrlfrllkmsginfvanplvnihlqgrfdtypkrrgit
rvkemlesginvcfghdgvfdpwyplgtanmlqvlhmglhvcqlmgygqindglnlithh
sartlnlqdygiaagnsanliilpaengfdalrrqvpvrysvrggkviastqpaqttvyl
eqpeaidykr

    Sequence, based on observed residues (ATOM records): (download) 
    >1ra0A (A:)
alqtiinarlpgeeglwqihlqdgkisaidaqsgvmpitensldaeqglvippfvephih
ldttqtagqpnwnqsgtlfegierwaerkallthddvkqrawqtlkwqiangiqhvrthv
dvsdatltalkamlevkqevapwidlqivafpqegilsypngealleealrlgadvvgai
phfeftreygveslhktfalaqkydrlidvhcdeiddeqsrfvetvaalahhegmgarvt
ashttamhsyngaytsrlfrllkmsginfvanplvnihlqgrfdtypkrrgitrvkemle
sginvcfghdgvfdpwyplgtanmlqvlhmglhvcqlmgygqindglnlithhsartlnl
qdygiaagnsanliilpaengfdalrrqvpvrysvrggkviastqpaqttvyleqpeaid
ykr