PDB entry 1q3a

View 1q3a on RCSB PDB site
Description: Crystal structure of the catalytic domain of human matrix metalloproteinase 10
Class: hydrolase
Keywords: MMP-10, metalloproteinase, inhibitors, NNGH, stromelysin-2, hydroxamic acid, HYDROLASE
Deposited on 2003-07-29, released 2004-04-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Stromelysin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP10 OR STMY2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09238 (Start-164)
      • engineered (71)
    Domains in SCOPe 2.08: d1q3aa_
  • Chain 'B':
    Compound: Stromelysin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP10 OR STMY2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09238 (Start-164)
      • engineered (71)
    Domains in SCOPe 2.08: d1q3ab_
  • Chain 'C':
    Compound: Stromelysin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP10 OR STMY2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09238 (Start-164)
      • engineered (71)
    Domains in SCOPe 2.08: d1q3ac_
  • Heterogens: ZN, CA, NGH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q3aA (A:)
fssfpgmpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadi
misfavkehgdnysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahe
lghslglfhsantealmyplynsftelaqfrlsqddvngiqslyg

    Sequence, based on observed residues (ATOM records): (download) 
    >1q3aA (A:)
mpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadimisfav
kehgdnysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahelghslg
lfhsantealmyplynslaqfrlsqddvngiqslyg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q3aB (B:)
fssfpgmpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadi
misfavkehgdnysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahe
lghslglfhsantealmyplynsftelaqfrlsqddvngiqslyg

    Sequence, based on observed residues (ATOM records): (download) 
    >1q3aB (B:)
gmpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadimisfa
vkehgdnysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahelghsl
glfhsantealmyplynsftelaqfrlsqddvngiqslyg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1q3aC (C:)
fssfpgmpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadi
misfavkehgdnysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahe
lghslglfhsantealmyplynsftelaqfrlsqddvngiqslyg

    Sequence, based on observed residues (ATOM records): (download) 
    >1q3aC (C:)
pkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadimisfavk
ehgdnysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahelghslgl
fhsantealmyplynslaqfrlsqddvngiqslyg