PDB entry 1p7c

View 1p7c on RCSB PDB site
Description: Crystal Structure of HSV1-TK complexed with TP5A
Class: transferase
Keywords: P-loop, Lid, bisubstrate inhibitor, TRANSFERASE
Deposited on 2003-05-01, released 2003-11-04
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.244
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) [TaxId:10299]
    Gene: TK OR UL23
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1p7ca_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) [TaxId:10299]
    Gene: TK OR UL23
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1p7cb_
  • Heterogens: SO4, THM, T5A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1p7cA (A:)
qqeatevrpeqkmptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlga
setianiyttqhrldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshap
ppaltlifdrhpiaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrh
idrlakrqrpgerldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgae
pqsnagprphigdtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqsp
agcrdallqltsgmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1p7cA (A:)
kmptllrvyidgphgmgkttttqllvaldivyvpeprvlgasetianiyttqhrldqgei
sagdaavvmtsaqitmgmpyavtdavlaphiggeagpppaltlifdrhpiaallcypaar
ylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaair
rvygllantvrylqcggswredwgqlsggprphigdtlftlfrapellapngdlynvfaw
aldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfar
e

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1p7cB (B:)
qqeatevrpeqkmptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlga
setianiyttqhrldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshap
ppaltlifdrhpiaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrh
idrlakrqrpgerldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgae
pqsnagprphigdtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqsp
agcrdallqltsgmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1p7cB (B:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgagprphigdtlftlfrapell
apngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsi
pticdlartfaremgean