PDB entry 1oit
View 1oit on RCSB PDB site
Description: imidazopyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation
Class: kinase
Keywords: kinase, protein kinase
Deposited on
2003-06-24, released
2003-09-04
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.22661
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 1OIT
- Uniprot P24941 (Start-297)
Domains in SCOPe 2.02: d1oita_ - Heterogens: HDT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1oitA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglsfchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>1oitA (A:)
nfqkvekigegtygvvykarnklgevvalkkitaireisllkelnhpnivklldvihten
klylvfeflhqdlkkfmdasaltgiplpliksylfqllqglsfchshrvlhrdlkpqnll
integaikladfglaravvtlwyrapeillgckyystavdiwslgcifaemvtrralfpg
dseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsq
mlhydpnkrisakaalahpffqdvtkpvphlrl