PDB entry 1njc

View 1njc on RCSB PDB site
Description: thymidylate synthase, mutation, n229d with 2'-deoxycytidine 5'-monophosphate (dcmp)
Class: transferase (methyltransferase)
Keywords: transferase, methyltransferase, nucleotide biosynthesis, transferase (methyltransferase)
Deposited on 1996-01-23, released 1996-07-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.184
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Lactobacillus casei [TaxId:1582]
    Gene: N229D MUTANT OF CLONED L. CASE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00469 (0-315)
      • engineered (228)
    Domains in SCOPe 2.08: d1njca_
  • Heterogens: DCM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1njcA (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfdiasyallthlv
ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
llnydpypaikapvav