PDB entry 1mx0

View 1mx0 on RCSB PDB site
Description: Structure of topoisomerase subunit
Class: isomerase
Keywords: GHKL ATPase, topoisomerase, ISOMERASE
Deposited on 2002-10-01, released 2003-01-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.219
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207
      • modified residue (108)
      • modified residue (122)
      • see remark 999 (304)
      • modified residue (410)
      • modified residue (413)
      • see remark 999 (436)
      • modified residue (446)
    Domains in SCOPe 2.07: d1mx0a1, d1mx0a2, d1mx0a3
  • Chain 'B':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207
      • modified residue (108)
      • modified residue (122)
      • see remark 999 (304)
      • modified residue (410)
      • modified residue (413)
      • see remark 999 (436)
      • modified residue (446)
    Domains in SCOPe 2.07: d1mx0b1, d1mx0b2, d1mx0b3
  • Chain 'C':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207
      • modified residue (108)
      • modified residue (122)
      • see remark 999 (304)
      • modified residue (410)
      • modified residue (413)
      • see remark 999 (436)
      • modified residue (446)
    Domains in SCOPe 2.07: d1mx0c1, d1mx0c2, d1mx0c3
  • Chain 'D':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207
      • modified residue (108)
      • modified residue (122)
      • see remark 999 (304)
      • modified residue (410)
      • modified residue (413)
      • see remark 999 (436)
      • modified residue (446)
    Domains in SCOPe 2.07: d1mx0d1, d1mx0d2, d1mx0d3
  • Chain 'E':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207
      • modified residue (108)
      • modified residue (122)
      • see remark 999 (304)
      • modified residue (410)
      • modified residue (413)
      • see remark 999 (436)
      • modified residue (446)
    Domains in SCOPe 2.07: d1mx0e1, d1mx0e2, d1mx0e3
  • Chain 'F':
    Compound: Type II DNA topoisomerase VI subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O05207
      • modified residue (108)
      • modified residue (122)
      • see remark 999 (304)
      • modified residue (410)
      • modified residue (413)
      • see remark 999 (436)
      • modified residue (446)
    Domains in SCOPe 2.07: d1mx0f1, d1mx0f2, d1mx0f3
  • Heterogens: MG, NA, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mx0A (A:)
gamsakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpniki
tidliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavly
sqmhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipg
dwpkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdr
eeikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlve
tfkkyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvaf
ggsipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcst
kipyksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx0A (A:)
kekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidli
ddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhq
dkpieietspvnskriytfklkidinknepiivergsvenfhgtsvaisipgdwpkaksr
iyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikilin
nlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkyedf
rspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvge
epivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksag
kesiaevediekeiknalmevarklkqylsekrkeqeakkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1mx0B (B:)
gamsakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpniki
tidliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavly
sqmhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipg
dwpkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdr
eeikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlve
tfkkyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvaf
ggsipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcst
kipyksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx0B (B:)
kekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidli
ddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhq
dkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpka
ksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeiki
linnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkky
edfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsip
vgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyk
sagkesiaevediekeiknalmevarklkqylsek

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1mx0C (C:)
gamsakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpniki
tidliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavly
sqmhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipg
dwpkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdr
eeikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlve
tfkkyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvaf
ggsipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcst
kipyksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx0C (C:)
kekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidli
ddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhq
dkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpka
ksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeiki
linnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkky
edfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsip
vgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyk
sagkesiaevediekeiknalmevarklkqylsekrkeqeakkkll

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1mx0D (D:)
gamsakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpniki
tidliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavly
sqmhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipg
dwpkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdr
eeikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlve
tfkkyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvaf
ggsipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcst
kipyksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx0D (D:)
kekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidli
ddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhq
dkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpka
ksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeiki
linnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkky
edfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsip
vgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyk
sagkesiaevediekeiknalmevarklkqylsekrkeqea

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1mx0E (E:)
gamsakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpniki
tidliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavly
sqmhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipg
dwpkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdr
eeikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlve
tfkkyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvaf
ggsipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcst
kipyksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx0E (E:)
kekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidli
ddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhq
dkpieietspvnskriytfklkidinknepiivergsventfhgtsvaisipgdwpkaks
riyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikili
nnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkyed
frspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvg
eepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksa
gkesiaevediekeiknalmevarklkqylsekrke

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1mx0F (F:)
gamsakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpniki
tidliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavly
sqmhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipg
dwpkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdr
eeikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlve
tfkkyedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvaf
ggsipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcst
kipyksagkesiaevediekeiknalmevarklkqylsekrkeqeakkklla

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx0F (F:)
kekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidli
ddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhq
dkpieietspvskriytfklkidinknepiivergsventhgtsvaisipgdwpkaksri
yeyikrtyiitpyaefifkdpenvtyyprltnkipkppqevkphpygvdreeikilinnl
krdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkyedfrs
psadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvgeep
ivlryankipliydeksdviwkvveeldwkrygisdqyqmvvmvhlcstkipyksagkes
iaevediekeiknalmevarklkqylsekrkeqe