PDB entry 1ja1

View 1ja1 on RCSB PDB site
Description: CYPOR-Triple Mutant
Class: oxidoreductase
Keywords: NADPH-Cytochrome P450 Reductase, oxidoreductase
Deposited on 2001-05-29, released 2001-08-22
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.208
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nadph-cytochrome p450 reductase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00388 (Start-621)
      • engineered (400)
      • engineered (573)
      • engineered (618)
    Domains in SCOPe 2.02: d1ja1a1, d1ja1a2, d1ja1a3
  • Chain 'B':
    Compound: nadph-cytochrome p450 reductase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CYPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00388 (Start-621)
      • engineered (400)
      • engineered (573)
      • engineered (618)
    Domains in SCOPe 2.02: d1ja1b1, d1ja1b2, d1ja1b3
  • Heterogens: FAD, FMN, NAP, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ja1A (A:)
iqttappvkessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpee
ydladlsslpeidkslvvfcmatygegdptdnaqdfydwlqetdvdltgvkfavfglgnk
tyehfnamgkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveat
geessirqyelvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgt
erhlmhleldisdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesn
kkhpfpcpttyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkely
lswvvearrhilailqdypslrppidhlcellprlqaryyaiassskvhpnsvhicavav
eyeaksgrvnkgvatswlrakepagenggralvpmfvrksqfrlpfksttpvimvgpgtg
iapfmgfiqerawlreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafs
reqahkvyvqhllkrdrehlwkliheggahiyvagdarnmakdvqntfydivaefgpmeh
tqavdyvkklmtkgryslnvws

    Sequence, based on observed residues (ATOM records): (download) 
    >1ja1A (A:)
pvkessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladl
sslpeidkslvvfcmatygegdptdnaqdfydwlqetdvdltgvkfavfglgnktyehfn
amgkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveatgeessi
rqyelvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgterhlmh
leldisdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesnkkhpfp
cpttyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkelylswvve
arrhilailqdypslrppidhlcellprlqaryyaiassskvhpnsvhicavaveyeaks
grvnkgvatswlrakepagenggralvpmfvrksqfrlpfksttpvimvgpgtgiapfmg
fiqerawlreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafsreqahk
vyvqhllkrdrehlwkliheggahiyvagdarnmakdvqntfydivaefgpmehtqavdy
vkklmtkgryslnvws

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ja1B (B:)
iqttappvkessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpee
ydladlsslpeidkslvvfcmatygegdptdnaqdfydwlqetdvdltgvkfavfglgnk
tyehfnamgkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveat
geessirqyelvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgt
erhlmhleldisdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesn
kkhpfpcpttyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkely
lswvvearrhilailqdypslrppidhlcellprlqaryyaiassskvhpnsvhicavav
eyeaksgrvnkgvatswlrakepagenggralvpmfvrksqfrlpfksttpvimvgpgtg
iapfmgfiqerawlreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafs
reqahkvyvqhllkrdrehlwkliheggahiyvagdarnmakdvqntfydivaefgpmeh
tqavdyvkklmtkgryslnvws

    Sequence, based on observed residues (ATOM records): (download) 
    >1ja1B (B:)
kessfvekmkktgrniivfygsqtgtaeefanrlskdahrygmrgmsadpeeydladlss
lpeidkslvvfcmatygegdptdnaqdfydwlqetdvdltgvkfavfglgnktyehfnam
gkyvdqrleqlgaqrifelglgdddgnleedfitwreqfwpavceffgveatgeessirq
yelvvhedmdvakvytgemgrlksyenqkppfdaknpflaavtanrklnqgterhlmhle
ldisdskiryesgdhvavypandsalvnqigeilgadldvimslnnldeesnkkhpfpcp
ttyrtaltyylditnpprtnvlyelaqyasepseqehlhkmasssgegkelylswvvear
rhilailqdypslrppidhlcellprlqaryyaiassskvhpnsvhicavaveyeaksgr
vnkgvatswlrakepagenggralvpmfvrksqfrlpfksttpvimvgpgtgiapfmgfi
qerawlreqgkevgetllyygcrrsdedylyreelarfhkdgaltqlnvafsreqahkvy
vqhllkrdrehlwkliheggahiyvagdarnmakdvqntfydivaefgpmehtqavdyvk
klmtkgryslnvws