PDB entry 1hef

View 1hef on RCSB PDB site
Description: The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase-hydrolase inhibitor complex
Deposited on 1992-09-21, released 1994-05-31
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.159
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'E':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366 (0-98)
    • conflict (35)
  Domains in SCOPe 2.01: d1hefe_
• Chain 'I':
  Compound: skf 108738 peptide inhibitor
  Database cross-references and differences (RAF-indexed):
  • PDB 1HEF (0-4)
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hefE (E:)
  pqitlwqrplvtikiggqlkealldtgaddtvleenslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'I':
  No sequence available.