PDB entry 1gpz

View 1gpz on RCSB PDB site
Description: the crystal structure of the zymogen catalytic domain of complement protease c1r
Class: hydrolase
Keywords: hydrolase, activation, complement, innate immunity, modular structure, serine protease
Deposited on 2001-11-15, released 2002-07-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-12, with a file datestamp of 2017-07-07.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: complement c1r component
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00736 (0-End)
      • engineered mutation (156)
    Domains in SCOPe 2.07: d1gpza1, d1gpza2, d1gpza3
  • Chain 'B':
    Compound: complement c1r component
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00736 (0-End)
      • engineered mutation (156)
    Domains in SCOPe 2.07: d1gpzb1, d1gpzb2, d1gpzb3
  • Heterogens: NAG, FUC, MAN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gpzA (A:)
ikcpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtwhr
amprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtragsreseqgv
ytctaqgiwkneqkgekiprclpvcgkpvnpveqrqqiiggqkakmgnfpwqvftnihgr
gggallgdrwiltaahtlypkeheaqsnasldvflghtnveelmklgnhpirrvsvhpdy
rqdesynfegdiallelensvtlgpnllpiclpdndtfydlglmgyvsgfgvmeekiahd
lrfvrlpvanpqacenwlrgknrmdvfsqnmfcaghpslkqdacqgdsggvfavrdpntd
rwvatgivswgigcsrgygfytkvlnyvdwikkemeeed

    Sequence, based on observed residues (ATOM records): (download) 
    >1gpzA (A:)
ikcpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtwhr
amprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqteqgvytctaqg
iwkneqkgekiprclpvcgkpvnpveqrqqiiggqkakmgnfpwqvftnihgrgggallg
drwiltaahtlypkehasldvflghtnveelmklgnhpirrvsvhpdyrqdesynfegdi
allelensvtlgpnllpiclpdndtfydlglmgyvsgfgiahdlrfvrlpvanpqacens
qnmfcaghpslkqdacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyv
dwikkemee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gpzB (B:)
ikcpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtwhr
amprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtragsreseqgv
ytctaqgiwkneqkgekiprclpvcgkpvnpveqrqqiiggqkakmgnfpwqvftnihgr
gggallgdrwiltaahtlypkeheaqsnasldvflghtnveelmklgnhpirrvsvhpdy
rqdesynfegdiallelensvtlgpnllpiclpdndtfydlglmgyvsgfgvmeekiahd
lrfvrlpvanpqacenwlrgknrmdvfsqnmfcaghpslkqdacqgdsggvfavrdpntd
rwvatgivswgigcsrgygfytkvlnyvdwikkemeeed

    Sequence, based on observed residues (ATOM records): (download) 
    >1gpzB (B:)
ikcpqpktldeftiiqnlqpqyqfrdyfiatckqgyqliegnqvlhsftavcqddgtwhr
amprckikdcgqprnlpngdfrytttmgvntykariqyychepyykmqtgvytctaqgiw
kneqkgekiprclpvcgkpvnpveqrqqiiggqkakmgnfpwqvftnihgrgggallgdr
wiltaahtlypkehqsnasldvflghtnveelmklgnhpirrvsvhpdyrqdesynfegd
iallelensvtlgpnllpiclpdndtfydlglmgyvsgfgiahdlrfvrlpvanpqaceq
nmfcaghpslkqdacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyvd
wikkemee