PDB entry 1d9i

View 1d9i on RCSB PDB site
Description: structure of thrombin complexed with selective non-electophilic inhibitors having cyclohexyl moieties at p1
Class: hydrolase/hydrolase inhibitor
Keywords: globular, hydrolase-hydrolase inhibitor complex
Deposited on 1999-10-27, released 2000-10-30
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.153
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1d9ia_
  • Chain 'I':
    Compound: hirugen
    Species: Hirudo medicinalis, synthetic [TaxId:6421]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NA, 00P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1d9iA (A:)
adcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

    Sequence, based on observed residues (ATOM records): (download) 
    >1d9iA (A:)
adcglrplfekksledkterellesyidivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketgqpsv
lqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrw
yqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

  • Chain 'I':
    No sequence available.