PDB entry 1d1t

View 1d1t on RCSB PDB site
Description: mutant of human sigma alcohol dehydrogenase with leucine at position 141
Class: oxidoreductase
Keywords: rossmann or dinucleotide fold, oxidoreductase
Deposited on 1999-09-21, released 1999-09-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.216
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alcohol dehydrogenase class IV sigma chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40394 (1-372)
      • engineered (139)
    Domains in SCOPe 2.05: d1d1ta1, d1d1ta2
  • Chain 'B':
    Compound: alcohol dehydrogenase class IV sigma chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40394 (1-372)
      • engineered (139)
    Domains in SCOPe 2.05: d1d1tb1, d1d1tb2
  • Chain 'C':
    Compound: alcohol dehydrogenase class IV sigma chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40394 (1-372)
      • engineered (139)
    Domains in SCOPe 2.05: d1d1tc1, d1d1tc2
  • Chain 'D':
    Compound: alcohol dehydrogenase class IV sigma chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40394 (1-372)
      • engineered (139)
    Domains in SCOPe 2.05: d1d1td1, d1d1td2
  • Heterogens: ZN, ACT, CAC, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1d1tA (A:)
gtagkvikckaavlweqkqpfsieeievappktkevrikilatgicrtddhvikgtmvsk
fpvivgheatgivesigegvttvkpgdkviplflpqcrecnacrnpdgnlcirsditgrg
vladgttrftckgkpvhhflntstfteytvvdessvakiddaappekvcligcgfstgyg
aavktgkvkpgstcvvfglggvglsvimgcksagasriigidlnkdkfekamavgateci
spkdstkpisevlsemtgnnvgytfevighletmidalaschmnygtsvvvgvppsakml
tydpmllftgrtwkgcvfgglksrddvpklvteflakkfdldqlithvlpfkkisegfel
lnsgqsirtvltf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1d1tB (B:)
gtagkvikckaavlweqkqpfsieeievappktkevrikilatgicrtddhvikgtmvsk
fpvivgheatgivesigegvttvkpgdkviplflpqcrecnacrnpdgnlcirsditgrg
vladgttrftckgkpvhhflntstfteytvvdessvakiddaappekvcligcgfstgyg
aavktgkvkpgstcvvfglggvglsvimgcksagasriigidlnkdkfekamavgateci
spkdstkpisevlsemtgnnvgytfevighletmidalaschmnygtsvvvgvppsakml
tydpmllftgrtwkgcvfgglksrddvpklvteflakkfdldqlithvlpfkkisegfel
lnsgqsirtvltf

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1d1tC (C:)
gtagkvikckaavlweqkqpfsieeievappktkevrikilatgicrtddhvikgtmvsk
fpvivgheatgivesigegvttvkpgdkviplflpqcrecnacrnpdgnlcirsditgrg
vladgttrftckgkpvhhflntstfteytvvdessvakiddaappekvcligcgfstgyg
aavktgkvkpgstcvvfglggvglsvimgcksagasriigidlnkdkfekamavgateci
spkdstkpisevlsemtgnnvgytfevighletmidalaschmnygtsvvvgvppsakml
tydpmllftgrtwkgcvfgglksrddvpklvteflakkfdldqlithvlpfkkisegfel
lnsgqsirtvltf

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1d1tD (D:)
gtagkvikckaavlweqkqpfsieeievappktkevrikilatgicrtddhvikgtmvsk
fpvivgheatgivesigegvttvkpgdkviplflpqcrecnacrnpdgnlcirsditgrg
vladgttrftckgkpvhhflntstfteytvvdessvakiddaappekvcligcgfstgyg
aavktgkvkpgstcvvfglggvglsvimgcksagasriigidlnkdkfekamavgateci
spkdstkpisevlsemtgnnvgytfevighletmidalaschmnygtsvvvgvppsakml
tydpmllftgrtwkgcvfgglksrddvpklvteflakkfdldqlithvlpfkkisegfel
lnsgqsirtvltf