PDB entry 1cwk
View 1cwk on RCSB PDB site
Description: human cyclophilin a complexed with 1-(6,7-dihydro)mebmt 2-val 3-d-(2-s-methyl)sarcosine cyclosporin
Class: isomerase/immunosuppressant
Keywords: isomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin d, immunosuppressant, cyclophilin
Deposited on
1998-05-26, released
1998-07-15
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-07-27, with a file datestamp of
2011-07-22.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.165
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peptidyl-prolyl cis-trans isomerase A
Species: Homo sapiens [TaxId:9606]
Gene: CYCLOPHILIN
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1cwka_ - Chain 'C':
Compound: cyclosporin d
Species: Tolypocladium inflatum, synthetic [TaxId:29910]
Database cross-references and differences (RAF-indexed):
- NOR NOR00036 (0-10)
- engineered mutation (4)
- engineered mutation (6)
- Heterogens: HOH