Lineage for d1udua_ (1udu A:)

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)
  3. 360609Fold a.125: PDEase [48546] (1 superfamily)
    multihelical; can be divided into three subdomains
  4. 360610Superfamily a.125.1: PDEase [48547] (1 family) (S)
  5. 360611Family a.125.1.1: PDEase [48548] (4 protein domains)
    3',5'-cyclic-nucleotide phosphodiesterase, Pfam 00233
  6. 360664Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species)
  7. 360665Species Human (Homo sapiens) [TaxId:9606] [101440] (3 PDB entries)
  8. 360668Domain d1udua_: 1udu A: [99222]

Details for d1udua_

PDB Entry: 1udu (more details), 2.83 Å

PDB Description: Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis)

SCOP Domain Sequences for d1udua_:

Sequence, based on SEQRES records: (download)

>d1udua_ a.125.1.1 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens)}
trelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhevlc
rwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshdld
hrgvnnsyiqrsehplaqlychsimehhhfdqclmilnspgnqilsglsieeykttlkii
kqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqq
riaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealthvs
edcfplldgcrknrqkwqalaeqq

Sequence, based on observed residues (ATOM records): (download)

>d1udua_ a.125.1.1 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens)}
trelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhevlc
rwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshdld
hrgvnnsyychsimehhhfdqclmilnspgnqilsglsieeykttlkiikqailatdlal
yikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqqriaelvateff
dqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealthvsedcfplldgcr
knrqkwqalaeqq

SCOP Domain Coordinates for d1udua_:

Click to download the PDB-style file with coordinates for d1udua_.
(The format of our PDB-style files is described here.)

Timeline for d1udua_: