Lineage for d1udua_ (1udu A:)

  1. Root: SCOP 1.69
  2. 436025Class a: All alpha proteins [46456] (218 folds)
  3. 450552Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 450553Superfamily a.211.1: HD-domain/PDEase-like [109604] (2 families) (S)
  5. 450559Family a.211.1.2: PDEase [48548] (6 proteins)
    multihelical; can be divided into three subdomains
    3',5'-cyclic-nucleotide phosphodiesterase, Pfam 00233
  6. 450621Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species)
  7. 450622Species Human (Homo sapiens) [TaxId:9606] [101440] (7 PDB entries)
  8. 450630Domain d1udua_: 1udu A: [99222]

Details for d1udua_

PDB Entry: 1udu (more details), 2.83 Å

PDB Description: Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis)

SCOP Domain Sequences for d1udua_:

Sequence, based on SEQRES records: (download)

>d1udua_ a.211.1.2 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens)}
trelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhevlc
rwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshdld
hrgvnnsyiqrsehplaqlychsimehhhfdqclmilnspgnqilsglsieeykttlkii
kqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqq
riaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealthvs
edcfplldgcrknrqkwqalaeqq

Sequence, based on observed residues (ATOM records): (download)

>d1udua_ a.211.1.2 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens)}
trelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhevlc
rwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshdld
hrgvnnsyychsimehhhfdqclmilnspgnqilsglsieeykttlkiikqailatdlal
yikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqqriaelvateff
dqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealthvsedcfplldgcr
knrqkwqalaeqq

SCOP Domain Coordinates for d1udua_:

Click to download the PDB-style file with coordinates for d1udua_.
(The format of our PDB-style files is described here.)

Timeline for d1udua_: