SCOPe 2.04: Domain d1pwva3: 1pwv A:264-550

Lineage for d1pwva3 (1pwv A:264-550)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.166: ADP-ribosylation [56398] (1 superfamily)
   unusual fold

4. Superfamily d.166.1: ADP-ribosylation [56399] (8 families)

5. Family d.166.1.1: ADP-ribosylating toxins [56400] (10 proteins)

6. Protein Anthrax toxin lethal factor, middle domain [69845] (1 species)
   includes an all-alpha insert subdomain

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [69846] (9 PDB entries)

8. Domain d1pwva3: 1pwv A:264-550 [95252]
   Other proteins in same PDB: d1pwva1, d1pwva2, d1pwvb1, d1pwvb2
   complexed with an optimized peptide substrate (chains C and D) in the presence of zinc

Details for d1pwva3

PDB Entry: 1pwv, 2.85 Å

PDB Description: Crystal structure of Anthrax Lethal Factor wild-type protein complexed with an optimised peptide substrate.

PDB Compounds: (A:) Lethal Factor

SCOPe Domain Sequences for d1pwva3:

Sequence, based on SEQRES records:

>d1pwva3 d.166.1.1 (A:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkldi
qpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmni
nnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwri
qlspdtragylengklilqrnigleikdvqiikqsekeyiridakvv

Sequence, based on observed residues (ATOM records):

>d1pwva3 d.166.1.1 (A:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslplsekekeflkklkldiqpydinqrlqdtgglid
spsinldvrkqykrdiqnidallhqsigstlynkiylyenmninnltatlgadlvdstdn
tkinrgifnefkknfkysissnymivdinerpaldnerlkwriqlspdtragylengkli
lqrnigleikdvqiikqsekeyiridakvv

Timeline for d1pwva3:

• d1pwva3 first appeared in SCOP 1.67
  
• d1pwva3 appears in SCOPe 2.03
  
• d1pwva3 appears in SCOPe 2.05
  
• d1pwva3 appears in the current release, SCOPe 2.08