SCOP 1.73: Domain d1o5za2: 1o5z A:-2-293

Lineage for d1o5za2 (1o5z A:-2-293)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.2: MurD-like peptide ligases, catalytic domain [53623] (2 families)
   has extra strand located between strands 1 and 2

5. Family c.72.2.2: Folylpolyglutamate synthetase [53629] (1 protein)

6. Protein Folylpolyglutamate synthetase [53630] (2 species)

7. Species Thermotoga maritima [TaxId:2336] [102644] (1 PDB entry)
   TM0166

8. Domain d1o5za2: 1o5z A:-2-293 [92531]
   Other proteins in same PDB: d1o5za1
   structural genomics
   complexed with cl, so4, unl

Details for d1o5za2

PDB Entry: 1o5z, 2.1 Å

PDB Description: crystal structure of folylpolyglutamate synthase (tm0166) from thermotoga maritima at 2.10 a resolution

PDB Compounds: (A:) folylpolyglutamate synthase/dihydrofolate synthase

SCOP Domain Sequences for d1o5za2:

Sequence, based on SEQRES records:

>d1o5za2 c.72.2.2 (A:-2-293) Folylpolyglutamate synthetase {Thermotoga maritima [TaxId: 2336]}
hhhmaylevlrylyhkrpmgkvkpglerismllsklgnphleyktihiggtngkgsvanm
vsnilvsqgyrvgsyysphlstfrerirlneeyiseedvvkiyetmepilneldkeeifs
psffevvtamaflyfaeknvdiavlevglggrldatnvvfplcstivtvdrdhektlgyt
ieqiaweksgiikervplvtgerkrealkvmedvarkkssrmyvidkdfsvkvkslklhe
nrfdycgentfedlvltmngphqienagvalktleatglplsekaireglknaknl

Sequence, based on observed residues (ATOM records):

>d1o5za2 c.72.2.2 (A:-2-293) Folylpolyglutamate synthetase {Thermotoga maritima [TaxId: 2336]}
hhhmaylevlrylyhkvkpglerismllsklgnphleyktihiggtngkgsvanmvsnil
vsqgyrvgsyysphlstfrerirlneeyiseedvvkiyetmepilneldkeeifspsffe
vvtamaflyfaeknvdiavlevglggrldatnvvfplcstivtvdrytieqiaweksgii
kervplvtgerkrealkvmedvarkkssrmyvidkdfsvkvkslklhenrfdycgentfe
dlvltmngphqienagvalktleatglplsekaireglknaknl

Timeline for d1o5za2:

• d1o5za2 first appeared in SCOP 1.67
  
• d1o5za2 appears in SCOP 1.71
  
• d1o5za2 appears in SCOP 1.75
  
• d1o5za2 appears in the current release, SCOPe 2.08