SCOP 1.75: Domain d1nhxa1: 1nhx A:260-622

Lineage for d1nhxa1 (1nhx A:260-622)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.91: PEP carboxykinase-like [53794] (1 superfamily)
   contains a P-loop NTP-binding motif; mixed beta-sheet folds into a barrel-like structure with helices packed on one side

4. Superfamily c.91.1: PEP carboxykinase-like [53795] (2 families)

5. Family c.91.1.1: PEP carboxykinase C-terminal domain [53796] (2 proteins)

6. Protein Cytosolic phosphoenolpyruvate carboxykinase (GTP-hydrolyzing) [69612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69613] (7 PDB entries)

8. Domain d1nhxa1: 1nhx A:260-622 [91886]
   Other proteins in same PDB: d1nhxa2
   complexed with edo, ftb, mn, na, pep

Details for d1nhxa1

PDB Entry: 1nhx, 2.1 Å

PDB Description: pepck complex with a gtp-competitive inhibitor

PDB Compounds: (A:) Phosphoenolpyruvate carboxykinase, cytosolic

SCOP Domain Sequences for d1nhxa1:

Sequence, based on SEQRES records:

>d1nhxa1 c.91.1.1 (A:260-622) Cytosolic phosphoenolpyruvate carboxykinase (GTP-hydrolyzing) {Human (Homo sapiens) [TaxId: 9606]}
wlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvgddiawmkfda
qghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvywegideplas
gvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpiegiifggrrpa
gvplvyealswqhgvfvgaamrseataaaehkgkiimhdpfamrpffgynfgkylahwls
maqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgkastkltpigyip
kedalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqri
sqm

Sequence, based on observed residues (ATOM records):

>d1nhxa1 c.91.1.1 (A:260-622) Cytosolic phosphoenolpyruvate carboxykinase (GTP-hydrolyzing) {Human (Homo sapiens) [TaxId: 9606]}
wlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvgddiawmkfda
qghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvywegideplas
gvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpiegiifggrrpa
gvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahwlsmaqhpaak
lpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgkastkltpigyipkedalnlk
glghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqrisqm

Timeline for d1nhxa1:

• d1nhxa1 first appeared in SCOP 1.67
  
• d1nhxa1 appears in SCOP 1.73
  
• d1nhxa1 appears in SCOPe 2.01
  
• d1nhxa1 appears in the current release, SCOPe 2.08