PDB entry 1nhx

View 1nhx on RCSB PDB site
Description: pepck complex with a GTP-competitive inhibitor
Class: lyase
Keywords: gluconeogenesis, xanthine, inhibitor
Deposited on 2002-12-19, released 2003-09-30
The last revision prior to the SCOP 1.75 freeze date was dated 2003-09-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.175
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoenolpyruvate carboxykinase, cytosolic
    Species: HOMO SAPIENS
    Gene: PCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35558 (Start-624)
      • variant (269)
      • variant (588)
      • variant (599)
    Domains in SCOP 1.75: d1nhxa1, d1nhxa2
  • Heterogens: MN, NA, PEP, FTB, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nhxA (A:)
gelmppqlqnglnlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrll
gqmeeegilrrlkkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwm
seedfekafnarfpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmg
tpvlealgdgefvkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgygg
nsllgkkcfalrmasrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammn
pslpgwkvecvgddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntif
tnvaetsdggvywegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiid
aawespegvpiegiifggrrpagvplvyealswqhgvfvgaamrseataaaehkgkiimh
dpfamrpffgynfgkylahwlsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvl
ewmfnridgkastkltpigyipkedalnlkglghinmmelfsiskefwdkevediekylv
dqvnadlpceiereilalkqrisqm

    Sequence, based on observed residues (ATOM records): (download) 
    >1nhxA (A:)
nlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrllgqmeeegilrrl
kkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwmseedfekafnar
fpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmgtpvlealgdgef
vkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgyggnsllgkkcfalr
masrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvg
ddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvy
wegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpie
giifggrrpagvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahw
lsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgkastkltpigy
ipkedalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkq
risqm